Ice · Remembrance
Evernight
Evernight and her memosprite both scale on Max HP and both pay HP to hit harder, so the healer is load-bearing and the buffs go to memosprite CRIT DMG.

Amphoreus
English voice: Aiden Dawn
No team on the site is built around Cyrene. The best team that wants Cyrene is Evernight's: Evernight, Cyrene, Sunday and Hyacine (Ice · Remembrance). Updated November 8, 2026
Ice · Remembrance
Evernight and her memosprite both scale on Max HP and both pay HP to hit harder, so the healer is load-bearing and the buffs go to memosprite CRIT DMG.
Quantum · Remembrance
Two Remembrance carries and Cyrene, whose Zone adds True DMG to every hit and whose Ultimate activates the team’s Ultimates. Hyacine heals the HP both carries spend. Run in 28.7% of clears across the four endgame modes in 4.6.
Ice · Remembrance
Two Remembrance supports in place of a Harmony unit: Cyrene’s Zone adds True DMG to each hit, and the Trailblazer’s Mem charges from the Energy the team regenerates. Hyacine covers the HP Evernight pays. Run in 0.8% of clears across the four endgame modes in 4.6.
Wind · Erudition
Anaxa’s hits plant Weaknesses of every Type. Cerydra’s Military Merit adds ATK and extra Wind hits after his attacks, Cyrene’s Zone adds True DMG to each instance, and Dan Heng • Permansor Terrae shields. Run in 0.5% of clears across the four endgame modes in 4.6.
Imaginary · HP scaling
Two Remembrance supports: Cyrene’s Zone adds True DMG to his hits and Robin • Summeretto’s Ultimate advances him. Hyacine heals the HP he spends. Run in 0.2% of clears across the four endgame modes in 4.6.
Imaginary · HP scaling
Cyrene and Tribbie as the two supports, Cyrene adding True DMG to each hit, and Hyacine healing the HP his attacks cost. Run in 0.2% of clears across the four endgame modes in 4.6.
Lightning · Remembrance
Cyrene’s Zone adds True DMG to every hit her memosprite lands and Robin • Summeretto’s Ultimate advances Aglaea. Hyacine heals. Run in 0.1% of clears across the four endgame modes in 4.6.
Lightning · Remembrance
The same Remembrance pair with Dan Heng • Permansor Terrae’s shields as the sustain.
Physical · Destruction
Two Harmony units on Phainon and Dan Heng • Permansor Terrae in place of a healer, shielding all four and naming one ally his Bondmate. Run in 1.9% of clears across the four endgame modes in 4.6.
Physical · Destruction
Three Harmony units and no sustain: Cerydra’s Military Merit, Sunday’s action advance and Sparkle’s CRIT DMG all go into one Destruction carry. Run in 1.7% of clears across the four endgame modes in 4.6.
Quantum · Remembrance
Castorice and Evernight with Cipher in Cyrene’s slot, a Nihility debuffer whose Weaken cuts the damage enemies deal while both carries spend HP.
No team on the site is built around Cyrene. The best team that wants Cyrene is Evernight's: Evernight, Cyrene, Sunday and Hyacine (Ice · Remembrance). Evernight and her memosprite both scale on Max HP and both pay HP to hit harder, so the healer is load-bearing and the buffs go to memosprite CRIT DMG.
Every Cyrene team listed here has at least one 5-star teammate. The replacements under each slot are the place to look for a 4-star that can stand in.